SAT0585 GEO-EPIDEMIOLOGY OF AUTOANTIBODIES IN RA: DIFFERENT PREVALENCES IN FOUR ETHNICALLY DIVERSE RA POPULATIONS

Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA.

INTRODUCTION Studies suggest that respiratory exposures including smoking, proximity to traffic and air pollution might be associated with development of rheumatoid arthritis (RA). RA-related autoantibodies are predictive of the development of RA. OBJECTIVE We evaluated the relationship between RA-related autoantibodies and exposure to particulate matter (PM), a measure of air pollution of in...

ra ins of Mice at Different Ages

We have recently been able to improve the conditions for in vitro lymphocyte cultures such that every growth-inducible murine B cell, in the presence of a Bcell mitogen, will initiate growth and maturation to IgM-, IgG-, and IgAsecreting plaque-forming cells (PFC) (1, 2). 1 This was achieved mainly by adding 2-mercaptoethanol (3), a growth-supporting fetal calf serum (4), growthsupporting thymu...

Hypoxia in RA

Introduction Maintaining oxygen homeostasis is of vital importance for the survival and development of mammalian cells. Hypoxia (below-normal levels of oxygen in air, blood and tissue) can potentially lead to cellular dysfunction and ultimately cell death and is a feature of many pathological conditions. Understanding how reduced oxygen levels may contribute to or even promote disease is a sign...

Circadian rhythms in RA.

Productivity loss due to absenteeism and presenteeism by different instruments in patients with RA and subjects without RA.

OBJECTIVES To explore the impact of at-work productivity loss on the total productivity cost by different instruments in patients recently diagnosed with RA and controls without RA. METHODS Cross-sectional data were collected from outpatients with RA between December 2007 and February 2008. The control group was formed by subjects without RA matched on age and gender. Absenteeism and presente...